Buice met with Clemson Head Coach Dabo Swinney on Monday.
"We hate to see Demont leave our program," said Swinney. "We were pleased with his progress, but he wants more immediate playing time so he will transfer at the end of the semester. We have granted him a release and wish him the best."
Buice, who came to Clemson from Gaston High School in Gadsden, AL, red-shirted the 2010 season. He had an outstanding spring game with 102 yards on 18 carries.
He missed the Troy game, the season opener this year with an injury, then played each of the last five games on special teams and had two tackles.